Adult:
10-50 mmol daily, adjusted according to patient's needs
Intravenous
SEVERE ACUTE HYPOCALCAEMIA OR HYPOCALCAEMIC TETANY
Adult:
2.25 mmol by slow IV inj over 10 min, followed by 58-77 ml of 10% calcium gluconate solution in 0.5-1L of 5% dextrose solution as continuous IV infusion.
Intravenous
SEVERE ACUTE HYPOCALCAEMIA OR HYPOCALCAEMIC TETANY
Adult:
Neonate and 1 mth–18 yr: 0.5 ml/kg of 10% calcium gluconate solution as a single dose. Max: 20 ml of 10% calcium gluconate solution.
Intravenous
ANTIDOTE IN SEVERE HYPERMAGNESAEMIA
Adult:
10 ml of 10% calcium gluconate solution over 2 min, repeated every 10 min if needed.
Intravenous
ANTIDOTE IN SEVERE HYPERMAGNESAEMIA
Adult:
Neonate and 1 mth-18 yr: 0.5 ml/kg of 10% calcium gluconate solution as a single dose. Max: 20 ml of 10% calcium gluconate solution.
Intravenous
SEVERE HYPERKALAEMIA
Adult:
10 ml of 10% calcium gluconate solution over 2 min, repeated every 10 min if needed
Intravenous
SEVERE HYPERKALAEMIA
Child:
Neonate and 1 mth-18 yr: 0.5 ml/kg of 10% calcium gluconate solution as a single dose. Max: 20 ml of 10% calcium gluconate solution.
Precautions
Impaired renal function; cardiac disease; hypercalcaemia-associated diseases, e.g. sarcoidosis; other malignancies. Pregnancy.
Potentially Life-threatening
Adverse Drug Reactions
GI irritation; soft-tissue calcification, skin sloughing or necrosis after IM/SC inj. Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation.
Adverse Drug Reactions
Cardiac arrhythmias and coma.
Interactions
Co-admin of high calcium doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vitamin D metabolite).
